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How much do smear-negative patients really contribute to tuberculosis transmissions? Re-examining an old question with new tools
BACKGROUND: Sputum smear microscopy is a common surrogate for tuberculosis infectiousness. Previous estimates that smear-negative patients contribute 13–20% of transmissions and are, on average, 20 to 25% as infectious as smear-positive cases are understood to be high. Herein, we use an ideal real-w...
Autores principales: | Asadi, Leyla, Croxen, Matthew, Heffernan, Courtney, Dhillon, Mannat, Paulsen, Catherine, Egedahl, Mary Lou, Tyrrell, Greg, Doroshenko, Alexander, Long, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743225/ https://www.ncbi.nlm.nih.gov/pubmed/35036885 http://dx.doi.org/10.1016/j.eclinm.2021.101250 |
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