Mice Lacking Gpr75 are Hypophagic and Thin

PURPOSE: Humans with haploinsufficiency of GPR75, an orphan GPCR, are thin. Gpr75 knockout (KO) mice are also thin with improved glucose homeostasis. We wanted to confirm these findings in Gpr75 KO mice and determine whether decreased energy intake and/or increased energy expenditure contributed to...

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Detalles Bibliográficos
Autores principales: Powell, David R, Doree, Deon D, DaCosta, Christopher M, Platt, Kenneth A, Brommage, Robert, Buhring, Lindsey, Revelli, Jean-Pierre, Shadoan, Melanie K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743382/
https://www.ncbi.nlm.nih.gov/pubmed/35023939
http://dx.doi.org/10.2147/DMSO.S342799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743382/
https://www.ncbi.nlm.nih.gov/pubmed/35023939
http://dx.doi.org/10.2147/DMSO.S342799

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