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Real-time digital polymerase chain reaction (PCR) as a novel technology improves limit of detection for rare allele assays

BACKGROUND: Tumor heterogeneity may lead to false negative test results for tissue biopsy-based companion diagnostic tests. Real-time polymerase chain reaction (PCR) and digital PCR assays are used to detect rare alleles in cell-free circulating DNA for liquid biopsies; however, those tests lack str...

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Detalles Bibliográficos
Autores principales:	Xu, Jiachen, Duong, Kyra, Yang, Zhenlin, Kaji, Kavanaugh, Ou, Jiajia, Head, Steven R., Crynen, Gogce, Ordoukhanian, Phillip, Hanna, Lauren, Hanna, Ava, Wang, Yan, Wang, Zhijie, Wang, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743530/ https://www.ncbi.nlm.nih.gov/pubmed/35070745 http://dx.doi.org/10.21037/tlcr-21-728

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