Genome editing reveals that pSCL4 is required for chromosome linearity in Streptomyces clavuligerus

Streptomyces clavuligerus is an industrially important actinomycete whose genetic manipulation is limited by low transformation and conjugation efficiencies, low levels of recombination of introduced DNA, and difficulty in obtaining consistent sporulation. We describe the construction and applicatio...

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Detalles Bibliográficos
Autores principales: Gomez-Escribano, Juan Pablo, Algora Gallardo, Lis, Bozhüyük, Kenan A. J., Kendrew, Steven G., Huckle, Benjamin D., Crowhurst, Nicola A., Bibb, Mervyn J., Collis, Andrew J., Micklefield, Jason, Herron, Paul R., Wilkinson, Barrie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743545/
https://www.ncbi.nlm.nih.gov/pubmed/34747689
http://dx.doi.org/10.1099/mgen.0.000669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743545/
https://www.ncbi.nlm.nih.gov/pubmed/34747689
http://dx.doi.org/10.1099/mgen.0.000669

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