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Comprehensive and accurate genetic variant identification from contaminated and low-coverage Mycobacterium tuberculosis whole genome sequencing data

Improved understanding of the genomic variants that allow Mycobacterium tuberculosis (Mtb) to acquire drug resistance, or tolerance, and increase its virulence are important factors in controlling the current tuberculosis epidemic. Current approaches to Mtb sequencing, however, cannot reveal Mtb’s f...

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Detalles Bibliográficos
Autores principales: Heupink, Tim H., Verboven, Lennert, Warren, Robin M., Van Rie, Annelies
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743552/
https://www.ncbi.nlm.nih.gov/pubmed/34793294
http://dx.doi.org/10.1099/mgen.0.000689