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Genome evolution drives transcriptomic and phenotypic adaptation in Pseudomonas aeruginosa during 20 years of infection

The opportunistic pathogen Pseudomonas aeruginosa chronically infects the lungs of patients with cystic fibrosis (CF). During infection the bacteria evolve and adapt to the lung environment. Here we use genomic, transcriptomic and phenotypic approaches to compare multiple isolates of P. aeruginosa c...

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Detalles Bibliográficos
Autores principales: Wardell, Samuel J.T., Gauthier, Jeff, Martin, Lois W., Potvin, Marianne, Brockway, Ben, Levesque, Roger C., Lamont, Iain L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743555/
https://www.ncbi.nlm.nih.gov/pubmed/34826267
http://dx.doi.org/10.1099/mgen.0.000681