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The Effects of PPAR Agonists on Atherosclerosis and Nonalcoholic Fatty Liver Disease in ApoE(−/−)FXR(−/−) Mice

BACKGROUND: Farnesoid X receptor (FXR), a bile acid–activated nuclear receptor, is a potent regulator of glucose and lipid metabolism as well as of bile acid metabolism. Previous studies have demonstrated that FXR deficiency is associated with metabolic derangements, including atherosclerosis and no...

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Detalles Bibliográficos
Autores principales: Lee, Yenna, Kim, Bo-Rahm, Kang, Geun-Hyung, Lee, Gwan Jae, Park, Young Joo, Kim, Haeryoung, Jang, Hak Chul, Choi, Sung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Endocrine Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743579/
https://www.ncbi.nlm.nih.gov/pubmed/34986301
http://dx.doi.org/10.3803/EnM.2021.1100