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The Effects of PPAR Agonists on Atherosclerosis and Nonalcoholic Fatty Liver Disease in ApoE(−/−)FXR(−/−) Mice
BACKGROUND: Farnesoid X receptor (FXR), a bile acid–activated nuclear receptor, is a potent regulator of glucose and lipid metabolism as well as of bile acid metabolism. Previous studies have demonstrated that FXR deficiency is associated with metabolic derangements, including atherosclerosis and no...
Autores principales: | Lee, Yenna, Kim, Bo-Rahm, Kang, Geun-Hyung, Lee, Gwan Jae, Park, Young Joo, Kim, Haeryoung, Jang, Hak Chul, Choi, Sung Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Endocrine Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743579/ https://www.ncbi.nlm.nih.gov/pubmed/34986301 http://dx.doi.org/10.3803/EnM.2021.1100 |
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