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CD73 Attenuates Alcohol-Induced Liver Injury and Inflammation via Blocking TLR4/MyD88/NF-κB Signaling Pathway

BACKGROUND: Alcoholic liver disease (ALD) is liver damage caused by long-term drinking. Inflammation plays a central role in the progression of ALD. CD73 is a ubiquitously expressed glycosylphosphatidylinositol-anchored glycoprotein that is a key enzyme that converts ATP into adenosine. Evidence has...

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Detalles Bibliográficos
Autores principales: Liu, Zhen-Ni, Wu, Xue, Fang, Qian, Li, Zi-Xuan, Xia, Guo-Qing, Cai, Jun-Nan, Lv, Xiong-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743621/
https://www.ncbi.nlm.nih.gov/pubmed/35023943
http://dx.doi.org/10.2147/JIR.S341680