Colistin resistance in Escherichia coli confers protection of the cytoplasmic but not outer membrane from the polymyxin antibiotic

Colistin is a polymyxin antibiotic of last resort for the treatment of infections caused by multi-drug-resistant Gram-negative bacteria. By targeting lipopolysaccharide (LPS), the antibiotic disrupts both the outer and cytoplasmic membranes, leading to bacterial death and lysis. Colistin resistance...

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Detalles Bibliográficos
Autores principales: Humphrey, Madeleine, Larrouy-Maumus, Gerald J., Furniss, R. Christopher D., Mavridou, Despoina A. I., Sabnis, Akshay, Edwards, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Antimicrobials and AMR
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743629/
https://www.ncbi.nlm.nih.gov/pubmed/34723787
http://dx.doi.org/10.1099/mic.0.001104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743629/
https://www.ncbi.nlm.nih.gov/pubmed/34723787
http://dx.doi.org/10.1099/mic.0.001104

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