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The deacetylation of Foxk2 by Sirt1 reduces chemosensitivity to cisplatin

In multiple types of cancer, decreased tumour cell apoptosis during chemotherapy is indicative of decreased chemosensitivity. Forkhead box K2 (FOXK2), which is essential for cell fate, regulates cancer cell apoptosis through several post‐translational modifications. However, FOXK2 acetylation has no...

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Detalles Bibliográficos
Autores principales: Wang, Xi‐wen, Guo, Qi‐qiang, Yu, Yang, Zhou, Ting‐ting, Zhang, Si‐yi, Wang, Zhuo, Liu, Jing‐wei, Tang, Jun, Jiang, Xiao‐you, Wang, Shan‐shan, Guo, Wen‐dong, Xu, Hong‐de, Sun, Hua‐yi, Li, Zi‐wei, Song, Xiao‐yu, Zhao, Jun‐gang, Cao, Liu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743664/
https://www.ncbi.nlm.nih.gov/pubmed/34866322
http://dx.doi.org/10.1111/jcmm.17107