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Tacrolimus alleviates LPS‐induced AKI by inhibiting TLR4/MyD88/NF‐κB signalling in mice

Lipopolysaccharide (LPS)‐induced sepsis‐associated acute kidney injury (SA‐AKI) is a model of clinical serious care syndrome, with high morbidity and mortality. Tacrolimus (TAC), a novel immunosuppressant that inhibits inflammatory response, plays a pivotal role in kidney diseases. In this study, LP...

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Detalles Bibliográficos
Autores principales: Hu, Xueqing, Zhou, Wenqian, Wu, Shun, Wang, Rui, Luan, Zhiyong, Geng, Xin, Xu, Na, Zhang, Zhaoyong, Ruan, Zhenmin, Wang, Zenghui, Li, Furong, Yu, Chen, Ren, Hongqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743665/
https://www.ncbi.nlm.nih.gov/pubmed/34889045
http://dx.doi.org/10.1111/jcmm.17108