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Notoginsenoside R2 induces colonic microvascular injuries via regulating the Rap1GAP/PI3K/Akt signaling pathway

BACKGROUND: Notoginsenoside R2 (NGR2) is an important active saponin molecule of Panax Notoginseng (PN), but its effect on regulating angiogenesis is unclear. Here, we investigated the role of NGR2 in angiogenesis in vivo and in vitro. METHODS: NGR2 was administered to rats by intragastric administr...

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Detalles Bibliográficos
Autores principales: Tao, Ping, Lin, Jiang, Zhang, Beiping, Wang, Shiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743707/
https://www.ncbi.nlm.nih.gov/pubmed/35071437
http://dx.doi.org/10.21037/atm-21-5898