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IL-36β promotes anti-tumor effects in CD8(+) T cells by downregulating micro-RNA let-7c-5p

BACKGROUND: The anti-tumor effect of interleukin (IL)-36β-mediated activation of CD8(+) T cells has been reported, but the molecular mechanism is largely undefined. METHODS: The levels of IL-36β in pancreatic cancer were examined by quantitative real-time PCR (qRT-PCR) and immunohistochemical staini...

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Detalles Bibliográficos
Autores principales: Li, Dongbao, Huang, Yang, Yu, Zhuwen, Zhang, Jianglei, Hu, Chenrui, Bai, Yanjin, Wang, Jin, Zhang, Zhe, Ouyang, Jun, Zhou, Jin, Zhao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743712/
https://www.ncbi.nlm.nih.gov/pubmed/35071428
http://dx.doi.org/10.21037/atm-21-5991