Polo-like kinase 4 as a potential predictive biomarker of chemoradioresistance in locally advanced rectal cancer

BACKGROUND: Polo-like kinase 4 (PLK4) is a serine/threonine protein kinase located in the centriole of the chromosome during the cell cycle. PLK4 overexpression has been described in a variety of many common human epithelial tumors. Conversely, PLK4 acts as a haploinsufficient tumor suppressor in so...

Descripción completa

Detalles Bibliográficos
Autores principales: Oh, Hyunseung, Kim, Soon Gu, Bae, Sung Uk, Byun, Sang Jun, Kim, Shin, Lee, Jae-Ho, Hwang, Ilseon, Kwon, Sun Young, Lee, Hye Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pathologists/The Korean Society for Cytopathology 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743804/
https://www.ncbi.nlm.nih.gov/pubmed/34775733
http://dx.doi.org/10.4132/jptm.2021.10.07

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743804/
https://www.ncbi.nlm.nih.gov/pubmed/34775733
http://dx.doi.org/10.4132/jptm.2021.10.07

Ejemplares similares