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Polo-like kinase 4 as a potential predictive biomarker of chemoradioresistance in locally advanced rectal cancer

BACKGROUND: Polo-like kinase 4 (PLK4) is a serine/threonine protein kinase located in the centriole of the chromosome during the cell cycle. PLK4 overexpression has been described in a variety of many common human epithelial tumors. Conversely, PLK4 acts as a haploinsufficient tumor suppressor in so...

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Detalles Bibliográficos
Autores principales:	Oh, Hyunseung, Kim, Soon Gu, Bae, Sung Uk, Byun, Sang Jun, Kim, Shin, Lee, Jae-Ho, Hwang, Ilseon, Kwon, Sun Young, Lee, Hye Won
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Pathologists/The Korean Society for Cytopathology 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743804/ https://www.ncbi.nlm.nih.gov/pubmed/34775733 http://dx.doi.org/10.4132/jptm.2021.10.07

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