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ATP is an essential autocrine factor for pancreatic β‐cell signaling and insulin secretion

ATP has been previously identified as an autocrine signaling factor that is co‐released with insulin to modulate and propagate β‐cell activity within islets of Langerhans. Here, we show that β‐cell activity and insulin secretion essentially rely on the presence of extracellular ATP. For this, we mon...

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Detalles Bibliográficos
Autores principales: Hauke, Sebastian, Rada, Jona, Tihanyi, Gergely, Schilling, Danny, Schultz, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743876/
https://www.ncbi.nlm.nih.gov/pubmed/35001557
http://dx.doi.org/10.14814/phy2.15159