PIK3CA Mutations in Diffuse Gliomas: An Update on Molecular Stratification, Prognosis, Recurrence, and Aggressiveness

INTRODUCTION: PIK3CA is one of the most mutated oncogenes in solid tumors. In breast cancer (ER-positive, HER2-negative), these events represent a predictive biomarker of response to alpelisib. In glioblastomas (GBM), PIK3CA mutations were described as early constitutive events. Here, we investigate...

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Detalles Bibliográficos
Autores principales: Brito, Cheila, Tomás, Ana, Azevedo, Ana, Esteves, Susana, Mafra, Manuela, Roque, Lúcia, Pojo, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743979/
https://www.ncbi.nlm.nih.gov/pubmed/35023985
http://dx.doi.org/10.1177/11795549211068804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743979/
https://www.ncbi.nlm.nih.gov/pubmed/35023985
http://dx.doi.org/10.1177/11795549211068804

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