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Membrane attack complex (MAC) deposition in renal tubules is associated with interstitial fibrosis and tubular atrophy: a pilot study

INTRODUCTION: Treatment failures for lupus nephritis (LN) are high with 10%–30% of patients progressing to end-stage renal disease (ESRD) within 10 years. Interstitial fibrosis/tubular atrophy (IFTA) is a predictor of progression to ESRD. Prior studies suggest that tubulointerstitial injury secondar...

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Detalles Bibliográficos
Autores principales: Wang, Shudan, Wu, Ming, Chiriboga, Luis, Zeck, Briana, Goilav, Beatrice, Wang, Shuwei, Jimenez, Alejandra Londono, Putterman, Chaim, Schwartz, Daniel, Pullman, James, Broder, Anna, Belmont, H Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744090/
https://www.ncbi.nlm.nih.gov/pubmed/34996855
http://dx.doi.org/10.1136/lupus-2021-000576