Hydroxychloroquine PK and exposure-response in pregnancies with lupus: the importance of adherence for neonatal outcomes

OBJECTIVE: Evaluate the impact of pregnancy physiology and medication non-adherence on serum hydroxychloroquine (HCQ) pharmacokinetics (PK) and exposure-response in SLE. METHODS: We conducted a PK analysis using data from two observational pregnancy registries. We enrolled pregnant women with SLE ta...

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Detalles Bibliográficos
Autores principales: Balevic, Stephen J, Weiner, Daniel, Clowse, Megan E B, Eudy, Amanda M, Maharaj, Anil R, Hornik, Christoph P, Cohen-Wolkowiez, Michael, Gonzalez, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Reproductive health and APS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744126/
https://www.ncbi.nlm.nih.gov/pubmed/34996856
http://dx.doi.org/10.1136/lupus-2021-000602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744126/
https://www.ncbi.nlm.nih.gov/pubmed/34996856
http://dx.doi.org/10.1136/lupus-2021-000602

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