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Dimensionless parameter predicts bacterial prodrug success

Understanding mechanisms of antibiotic failure is foundational to combating the growing threat of multidrug‐resistant bacteria. Prodrugs—which are converted into a pharmacologically active compound after administration—represent a growing class of therapeutics for treating bacterial infections but a...

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Detalles Bibliográficos
Autores principales: Holt, Brandon Alexander, Tuttle, McKenzie, Xu, Yilin, Su, Melanie, Røise, Joachim J, Wang, Xioajian, Murthy, Niren, Kwong, Gabriel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744131/
https://www.ncbi.nlm.nih.gov/pubmed/35005851
http://dx.doi.org/10.15252/msb.202110495