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Dimensionless parameter predicts bacterial prodrug success
Understanding mechanisms of antibiotic failure is foundational to combating the growing threat of multidrug‐resistant bacteria. Prodrugs—which are converted into a pharmacologically active compound after administration—represent a growing class of therapeutics for treating bacterial infections but a...
Autores principales: | Holt, Brandon Alexander, Tuttle, McKenzie, Xu, Yilin, Su, Melanie, Røise, Joachim J, Wang, Xioajian, Murthy, Niren, Kwong, Gabriel A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744131/ https://www.ncbi.nlm.nih.gov/pubmed/35005851 http://dx.doi.org/10.15252/msb.202110495 |
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