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Hepatic stellate cell activation and senescence induced by intrahepatic microbiota disturbances drive progression of liver cirrhosis toward hepatocellular carcinoma

BACKGROUND: The significance of the relationship between the microbiota and diseases is increasingly being recognized. However, the characterization of tumor microbiome and their precise molecular mechanisms through which microbiota promotes hepatocellular carcinoma (HCC) development are still uncle...

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Detalles Bibliográficos
Autores principales: Liu, Boyuan, Zhou, Zewei, Jin, Yu, Lu, Jinying, Feng, Dongju, Peng, Rui, Sun, Hua, Mu, Xiaoxin, Li, Changxian, Chen, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744134/
https://www.ncbi.nlm.nih.gov/pubmed/34996812
http://dx.doi.org/10.1136/jitc-2021-003069