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Neurological management and work-up of neurotoxicity associated with CAR T cell therapy

INTRODUCTION: Treatment with CD19 chimeric antigen receptor (CAR) T cells is an innovative therapeutic approach for patients with relapsed/refractory diffuse large B cell lymphoma (r/rDLBCL) and B-lineage acute lymphoblastic leukemia (r/rALL). However, convincing therapeutic response rates can be ac...

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Detalles Bibliográficos
Autores principales: Möhn, Nora, Bonda, Viktoria, Grote-Levi, Lea, Panagiota, Victoria, Fröhlich, Tabea, Schultze-Florey, Christian, Wattjes, Mike P., Beutel, Gernot, Eder, Matthias, David, Sascha, Körner, Sonja, Höglinger, Günter, Stangel, Martin, Ganser, Arnold, Koenecke, Christian, Skripuletz, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744256/
https://www.ncbi.nlm.nih.gov/pubmed/35000613
http://dx.doi.org/10.1186/s42466-021-00166-5