RNA binding protein HuD promotes autophagy and tumor stress survival by suppressing mTORC1 activity and augmenting ARL6IP1 levels

BACKGROUND: Neuronal-origin HuD (ELAVL4) is an RNA binding protein overexpressed in neuroblastoma (NB) and certain other cancers. The RNA targets of this RNA binding protein in neuroblastoma cells and their role in promoting cancer survival have been unexplored. In the study of modulators of mTORC1...

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Detalles Bibliográficos
Autores principales: Bishayee, Kausik, Habib, Khadija, Nazim, Uddin Md., Kang, Jieun, Szabo, Aniko, Huh, Sung-Oh, Sadra, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744261/
https://www.ncbi.nlm.nih.gov/pubmed/35012594
http://dx.doi.org/10.1186/s13046-021-02203-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744261/
https://www.ncbi.nlm.nih.gov/pubmed/35012594
http://dx.doi.org/10.1186/s13046-021-02203-2

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