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Long read sequencing reveals novel isoforms and insights into splicing regulation during cell state changes

BACKGROUND: Alternative splicing is a key mechanism underlying cellular differentiation and a driver of complexity in mammalian neuronal tissues. However, understanding of which isoforms are differentially used or expressed and how this affects cellular differentiation remains unclear. Long read seq...

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Detalles Bibliográficos
Autores principales: Wright, David J., Hall, Nicola A. L., Irish, Naomi, Man, Angela L., Glynn, Will, Mould, Arne, Angeles, Alejandro De Los, Angiolini, Emily, Swarbreck, David, Gharbi, Karim, Tunbridge, Elizabeth M., Haerty, Wilfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744310/
https://www.ncbi.nlm.nih.gov/pubmed/35012468
http://dx.doi.org/10.1186/s12864-021-08261-2