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Long read sequencing reveals novel isoforms and insights into splicing regulation during cell state changes
BACKGROUND: Alternative splicing is a key mechanism underlying cellular differentiation and a driver of complexity in mammalian neuronal tissues. However, understanding of which isoforms are differentially used or expressed and how this affects cellular differentiation remains unclear. Long read seq...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744310/ https://www.ncbi.nlm.nih.gov/pubmed/35012468 http://dx.doi.org/10.1186/s12864-021-08261-2 |