Modification of mesenchymal stem cells by HMGB1 promotes the activity of Cav3.2 T-type calcium channel via PKA/β-catenin/γ-cystathionase pathway

BACKGROUND: Mesenchymal stem cells (MSC) hold great promise for treating cardiovascular disease. Recently, we genetically modified MSCs with high mobility group box 1 (HMGB1), and these cells demonstrated high mobility by efficient migrating and homing to target neointima. The possible mechanism was...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Hao, Xie, Xiaodong, Sun, Mingyang, Chen, Min, Tao, Xuan, Fang, Xin, Meng, Xiaohu, Wei, Wei, Yu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744322/
https://www.ncbi.nlm.nih.gov/pubmed/35012644
http://dx.doi.org/10.1186/s13287-021-02677-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744322/
https://www.ncbi.nlm.nih.gov/pubmed/35012644
http://dx.doi.org/10.1186/s13287-021-02677-z

Ejemplares similares