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Modification of mesenchymal stem cells by HMGB1 promotes the activity of Cav3.2 T-type calcium channel via PKA/β-catenin/γ-cystathionase pathway
BACKGROUND: Mesenchymal stem cells (MSC) hold great promise for treating cardiovascular disease. Recently, we genetically modified MSCs with high mobility group box 1 (HMGB1), and these cells demonstrated high mobility by efficient migrating and homing to target neointima. The possible mechanism was...
Autores principales: | Wu, Hao, Xie, Xiaodong, Sun, Mingyang, Chen, Min, Tao, Xuan, Fang, Xin, Meng, Xiaohu, Wei, Wei, Yu, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744322/ https://www.ncbi.nlm.nih.gov/pubmed/35012644 http://dx.doi.org/10.1186/s13287-021-02677-z |
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