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Bone mesenchymal stem cell-derived exosomal microRNA-7-5p inhibits progression of acute myeloid leukemia by targeting OSBPL11

BACKGROUND: Acute myeloid leukemia (AML) is a malignant clonal disease of hematopoietic stem- and progenitor-cell origin. AML features massive proliferation of abnormal blasts and leukemia cells in the bone marrow and the inhibition of normal hematopoiesis at onset. Exosomes containing proteins or n...

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Detalles Bibliográficos
Autores principales: Jiang, Duanfeng, Wu, Xin, Sun, Xiaoying, Tan, Wei, Dai, Xin, Xie, Youbang, Du, Ashuai, Zhao, Qiangqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744354/
https://www.ncbi.nlm.nih.gov/pubmed/35012554
http://dx.doi.org/10.1186/s12951-021-01206-7