Hi-C detects genomic structural variants in peripheral blood of pediatric leukemia patients

B-cell acute lymphoblastic leukemia (B-ALL) is often driven by chromosome translocations that result in recurrent and well-studied gene fusions. Currently, fluorescent in situ hybridization probes are used to detect candidate translocations in bone marrow samples from B-ALL patients. Recently Hi-C,...

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Detalles Bibliográficos
Autores principales: Mallard, Claire, Johnston, Michael J., Bobyn, Anna, Nikolic, Ana, Argiropoulos, Bob, Chan, Jennifer A., Guilcher, Gregory M.T., Gallo, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744495/
https://www.ncbi.nlm.nih.gov/pubmed/34819303
http://dx.doi.org/10.1101/mcs.a006157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744495/
https://www.ncbi.nlm.nih.gov/pubmed/34819303
http://dx.doi.org/10.1101/mcs.a006157

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