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The Sulfotransferase SULT1C2 Is Epigenetically Activated and Transcriptionally Induced by Tobacco Exposure and Is Associated with Patient Outcome in Lung Adenocarcinoma

Lung cancer is the leading cause of cancer-related death. Tobacco exposure is associated with 80–90% of lung cancer cases. The SULT1C2 sulfotransferase modifies xenobiotic compounds to enhance secretion but can also render these compounds carcinogenic. To determine if SULT1C2 contributes to tobacco-...

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Detalles Bibliográficos
Autores principales: Johnson, Candace, Mullen, Daniel J., Selamat, Suhaida A., Campan, Mihaela, Offringa, Ite A., Marconett, Crystal N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744592/
https://www.ncbi.nlm.nih.gov/pubmed/35010676
http://dx.doi.org/10.3390/ijerph19010416