Rare Trafficking CFTR Mutations Involve Distinct Cellular Retention Machineries and Require Different Rescuing Strategies

Most of the ~2100 CFTR variants so far reported are very rare and still uncharacterized regarding their cystic fibrosis (CF) disease liability. Since some may respond to currently approved modulators, characterizing their defect and response to these drugs is essential. Here we aimed characterizing...

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Detalles Bibliográficos
Autores principales: Ramalho, Sofia S., Silva, Iris A. L., Amaral, Margarida D., Farinha, Carlos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744605/
https://www.ncbi.nlm.nih.gov/pubmed/35008443
http://dx.doi.org/10.3390/ijms23010024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744605/
https://www.ncbi.nlm.nih.gov/pubmed/35008443
http://dx.doi.org/10.3390/ijms23010024

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