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MicroRNA 630 Represses NANOG Expression through Transcriptional and Post-Transcriptional Regulation in Human Embryonal Carcinoma Cells

The pluripotent transcription factor NANOG is essential for maintaining embryonic stem cells and driving tumorigenesis. We previously showed that PKC activity is involved in the regulation of NANOG expression. To explore the possible involvement of microRNAs in regulating the expression of key pluri...

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Detalles Bibliográficos
Autores principales: Chu, Wing-Keung, Hung, Li-Man, Hou, Chun-Wei, Chen, Jan-Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744645/
https://www.ncbi.nlm.nih.gov/pubmed/35008480
http://dx.doi.org/10.3390/ijms23010046