Cell type–specific analysis by single-cell profiling identifies a stable mammalian tRNA–mRNA interface and increased translation efficiency in neurons

The correlation between codon and anticodon pools influences the efficiency of translation, but whether differences exist in these pools across individual cells is unknown. We determined that codon usage and amino acid demand are highly stable across different cell types using available mouse and hu...

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Detalles Bibliográficos
Autores principales: Gao, William, Gallardo-Dodd, Carlos J., Kutter, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744671/
https://www.ncbi.nlm.nih.gov/pubmed/34857654
http://dx.doi.org/10.1101/gr.275944.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744671/
https://www.ncbi.nlm.nih.gov/pubmed/34857654
http://dx.doi.org/10.1101/gr.275944.121

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