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Meta-analysis of human and mouse ALS astrocytes reveals multi-omic signatures of inflammatory reactive states
Astrocytes contribute to motor neuron death in amyotrophic lateral sclerosis (ALS), but whether they adopt deleterious features consistent with inflammatory reactive states remains incompletely resolved. To identify inflammatory reactive features in ALS human induced pluripotent stem cell (hiPSC)–de...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744676/ https://www.ncbi.nlm.nih.gov/pubmed/34963663 http://dx.doi.org/10.1101/gr.275939.121 |