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Meta-analysis of human and mouse ALS astrocytes reveals multi-omic signatures of inflammatory reactive states

Astrocytes contribute to motor neuron death in amyotrophic lateral sclerosis (ALS), but whether they adopt deleterious features consistent with inflammatory reactive states remains incompletely resolved. To identify inflammatory reactive features in ALS human induced pluripotent stem cell (hiPSC)–de...

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Detalles Bibliográficos
Autores principales:	Ziff, Oliver J., Clarke, Benjamin E., Taha, Doaa M., Crerar, Hamish, Luscombe, Nicholas M., Patani, Rickie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744676/ https://www.ncbi.nlm.nih.gov/pubmed/34963663 http://dx.doi.org/10.1101/gr.275939.121

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