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Genomic environments scale the activities of diverse core promoters

A classical model of gene regulation is that enhancers provide specificity whereas core promoters provide a modular site for the assembly of the basal transcriptional machinery. However, examples of core promoter specificity have led to an alternate hypothesis in which specificity is achieved by cor...

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Detalles Bibliográficos
Autores principales: Hong, Clarice K.Y., Cohen, Barak A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744677/
https://www.ncbi.nlm.nih.gov/pubmed/34961747
http://dx.doi.org/10.1101/gr.276025.121