A full-proteome, interaction-specific characterization of mutational hotspots across human cancers

Rapid accumulation of cancer genomic data has led to the identification of an increasing number of mutational hotspots with uncharacterized significance. Here we present a biologically informed computational framework that characterizes the functional relevance of all 1107 published mutational hotsp...

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Detalles Bibliográficos
Autores principales: Chen, Siwei, Liu, Yuan, Zhang, Yingying, Wierbowski, Shayne D., Lipkin, Steven M., Wei, Xiaomu, Yu, Haiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744679/
https://www.ncbi.nlm.nih.gov/pubmed/34963661
http://dx.doi.org/10.1101/gr.275437.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744679/
https://www.ncbi.nlm.nih.gov/pubmed/34963661
http://dx.doi.org/10.1101/gr.275437.121

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