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Elevation of Hyaluronan Synthase by Magnesium Supplementation Mediated through the Activation of GSK3 and CREB in Human Keratinocyte-Derived HaCaT Cells

Skin barrier damage is present in the patients with hereditary disorders of the magnesium channel, but the molecular mechanism has not been fully understood. We found that the expressions of hyaluronan synthase (HAS), HAS2 and HAS3 are influenced by MgCl(2) concentration in human keratinocyte-derive...

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Detalles Bibliográficos
Autores principales: Marunaka, Kana, Shu, Shokoku, Kobayashi, Mao, Goto, Makiko, Katsuta, Yuji, Yoshino, Yuta, Ikari, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744730/
https://www.ncbi.nlm.nih.gov/pubmed/35008494
http://dx.doi.org/10.3390/ijms23010071