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The Non-Erythropoietic EPO Analogue Cibinetide Inhibits Osteoclastogenesis In Vitro and Increases Bone Mineral Density in Mice

The two erythropoietin (EPO) receptor forms mediate different cellular responses to erythropoietin. While hematopoiesis is mediated via the homodimeric EPO receptor (EPOR), tissue protection is conferred via a heteromer composed of EPOR and CD131. In the skeletal system, EPO stimulates osteoclast pr...

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Detalles Bibliográficos
Autores principales: Awida, Zamzam, Bachar, Almog, Saed, Hussam, Gorodov, Anton, Ben-Califa, Nathalie, Ibrahim, Maria, Kolomansky, Albert, Iden, Jennifer Ana, Graniewitz Visacovsky, Liad, Liron, Tamar, Hiram-Bab, Sahar, Brines, Michael, Gabet, Yankel, Neumann, Drorit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744753/
https://www.ncbi.nlm.nih.gov/pubmed/35008482
http://dx.doi.org/10.3390/ijms23010055