Anticonvulsive Effects and Pharmacokinetic Profile of Cannabidiol (CBD) in the Pentylenetetrazol (PTZ) or N-Methyl-D-Aspartate (NMDA) Models of Seizures in Infantile Rats

In spite of use of cannabidiol (CBD), a non-psychoactive cannabinoid, in pediatric patients with epilepsy, preclinical studies on its effects in immature animals are very limited. In the present study we investigated anti-seizure activity of CBD (10 and 60 mg/kg administered intraperitoneally) in tw...

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Detalles Bibliográficos
Autores principales: Uttl, Libor, Hložek, Tomáš, Mareš, Pavel, Páleníček, Tomáš, Kubová, Hana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744811/
https://www.ncbi.nlm.nih.gov/pubmed/35008517
http://dx.doi.org/10.3390/ijms23010094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744811/
https://www.ncbi.nlm.nih.gov/pubmed/35008517
http://dx.doi.org/10.3390/ijms23010094

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