Lucanthone, Autophagy Inhibitor, Enhances the Apoptotic Effects of TRAIL through miR-216a-5p-Mediated DR5 Upregulation and DUB3-Mediated Mcl-1 Downregulation

A lucanthone, one of the family of thioxanthenones, has been reported for its inhibitory effects of apurinic endonuclease-1 and autophagy. In this study, we investigated whether lucanthone could enhance tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in various canc...

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Detalles Bibliográficos
Autores principales: Yoon, Ji Yun, Woo, Seon Min, Seo, Seung Un, Song, So Rae, Lee, Seul Gi, Kwon, Taeg Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744864/
https://www.ncbi.nlm.nih.gov/pubmed/35008442
http://dx.doi.org/10.3390/ijms23010017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744864/
https://www.ncbi.nlm.nih.gov/pubmed/35008442
http://dx.doi.org/10.3390/ijms23010017

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