High-Dose Benzodiazepines Positively Modulate GABA(A) Receptors via a Flumazenil-Insensitive Mechanism

Benzodiazepines (BZDs) produce versatile pharmacological actions through positive modulation of GABA(A) receptors (GABA(A)Rs). A previous study has demonstrated that high concentrations of diazepam potentiate GABA currents on the α(1)β(2)γ(2) and α(1)β(2) GABA(A)Rs in a flumazenil-insensitive manner...

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Detalles Bibliográficos
Autores principales: Wang, Na, Lian, Jingjing, Cao, Yanqing, Muheyati, Alai, Yuan, Shanshan, Ma, Yujie, Zhang, Shuzhuo, Yu, Gang, Su, Ruibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744940/
https://www.ncbi.nlm.nih.gov/pubmed/35008465
http://dx.doi.org/10.3390/ijms23010042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744940/
https://www.ncbi.nlm.nih.gov/pubmed/35008465
http://dx.doi.org/10.3390/ijms23010042

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