A Quantitative Systems Approach to Define Novel Effects of Tumour p53 Mutations on Binding Oncoprotein MDM2

Understanding transient protein interactions biochemically at the proteome scale remains a long-standing challenge. Current tools developed to study protein interactions in high-throughput measure stable protein complexes and provide binary readouts; they do not elucidate dynamic and weak protein in...

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Detalles Bibliográficos
Autores principales: Fuentes, Manuel, Srivastava, Sanjeeva, Gronenborn, Angela M., LaBaer, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744954/
https://www.ncbi.nlm.nih.gov/pubmed/35008477
http://dx.doi.org/10.3390/ijms23010053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744954/
https://www.ncbi.nlm.nih.gov/pubmed/35008477
http://dx.doi.org/10.3390/ijms23010053

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