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Loss of αA or αB-Crystallin Accelerates Photoreceptor Cell Death in a Mouse Model of P23H Autosomal Dominant Retinitis Pigmentosa

Inherited retinal degenerations (IRD) are a leading cause of visual impairment and can result from mutations in any one of a multitude of genes. Mutations in the light-sensing protein rhodopsin (RHO) is a leading cause of IRD with the most common of those being a missense mutation that results in su...

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Detalles Bibliográficos
Autores principales: Wang, Tiantian, Yao, Jingyu, Jia, Lin, Fort, Patrice E., Zacks, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744961/
https://www.ncbi.nlm.nih.gov/pubmed/35008496
http://dx.doi.org/10.3390/ijms23010070