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Multi-Omics Profiling in Marfan Syndrome: Further Insights into the Molecular Mechanisms Involved in Aortic Disease

Thoracic aortic aneurysm is a potentially life-threatening disease with a strong genetic contribution. Despite identification of multiple genes involved in aneurysm formation, little is known about the specific underlying mechanisms that drive the pathological changes in the aortic wall. The aim of...

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Detalles Bibliográficos
Autores principales: Verhagen, Judith M. A., Burger, Joyce, Bekkers, Jos A., den Dekker, Alexander T., von der Thüsen, Jan H., Zajec, Marina, Brüggenwirth, Hennie T., van der Sterre, Marianne L. T., van den Born, Myrthe, Luider, Theo M., van IJcken, Wilfred F. J., Wessels, Marja W., Essers, Jeroen, Roos-Hesselink, Jolien W., van der Pluijm, Ingrid, van de Laar, Ingrid M. B. H., Brosens, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745050/
https://www.ncbi.nlm.nih.gov/pubmed/35008861
http://dx.doi.org/10.3390/ijms23010438