Biological Implications of a Stroke Therapy Based in Neuroglobin Hyaluronate Nanoparticles. Neuroprotective Role and Molecular Bases

Exogenous neuroprotective protein neuroglobin (Ngb) cannot cross the blood–brain barrier. To overcome this difficulty, we synthesized hyaluronate nanoparticles (NPs), able to deliver Ngb into the brain in an animal model of stroke (MCAO). These NPs effectively reached neurons, and were microscopical...

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Detalles Bibliográficos
Autores principales: Peinado, María Ángeles, Ovelleiro, David, del Moral, María Luisa, Hernández, Raquel, Martínez-Lara, Esther, Siles, Eva, Pedrajas, José Rafael, García-Martín, María Luisa, Caro, Carlos, Peralta, Sebastián, Morales, María Encarnación, Ruiz, María Adolfina, Blanco, Santos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745106/
https://www.ncbi.nlm.nih.gov/pubmed/35008673
http://dx.doi.org/10.3390/ijms23010247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745106/
https://www.ncbi.nlm.nih.gov/pubmed/35008673
http://dx.doi.org/10.3390/ijms23010247

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