Inhibition of Carbonic Anhydrase 2 Overcomes Temozolomide Resistance in Glioblastoma Cells

About 95% of Glioblastoma (GBM) patients experience tumor relapse as a consequence of resistance to the first-line standard chemotherapy using temozolomide (TMZ). Recent studies reported consistently elevated expression levels of carbonic anhydrase CA2 in recurrent glioblastoma and temozolomide-resi...

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Detalles Bibliográficos
Autores principales: Zhao, Kai, Schäfer, Agnes, Zhang, Zhuo, Elsässer, Katharina, Culmsee, Carsten, Zhong, Li, Pagenstecher, Axel, Nimsky, Christopher, Bartsch, Jörg W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745118/
https://www.ncbi.nlm.nih.gov/pubmed/35008590
http://dx.doi.org/10.3390/ijms23010157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745118/
https://www.ncbi.nlm.nih.gov/pubmed/35008590
http://dx.doi.org/10.3390/ijms23010157

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