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Inhibition of Carbonic Anhydrase 2 Overcomes Temozolomide Resistance in Glioblastoma Cells
About 95% of Glioblastoma (GBM) patients experience tumor relapse as a consequence of resistance to the first-line standard chemotherapy using temozolomide (TMZ). Recent studies reported consistently elevated expression levels of carbonic anhydrase CA2 in recurrent glioblastoma and temozolomide-resi...
Autores principales: | Zhao, Kai, Schäfer, Agnes, Zhang, Zhuo, Elsässer, Katharina, Culmsee, Carsten, Zhong, Li, Pagenstecher, Axel, Nimsky, Christopher, Bartsch, Jörg W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745118/ https://www.ncbi.nlm.nih.gov/pubmed/35008590 http://dx.doi.org/10.3390/ijms23010157 |
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