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In Vitro Propagation of XXY Undifferentiated Mouse Spermatogonia: Model for Fertility Preservation in Klinefelter Syndrome Patients

Klinefelter syndrome (KS) is characterized by a masculine phenotype, supernumerary sex chromosomes (usually XXY), and spermatogonial stem cell (SSC) loss in their early life. Affecting 1 out of every 650 males born, KS is the most common genetic cause of male infertility, and new fertility preservat...

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Detalles Bibliográficos
Autores principales: Galdon, Guillermo, Deebel, Nicholas A., Zarandi, Nima Pourhabibi, Pettenati, Mark J., Kogan, Stanley, Wang, Christina, Swerdloff, Ronald S., Atala, Anthony, Lue, Yanhe, Sadri-Ardekani, Hooman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745151/
https://www.ncbi.nlm.nih.gov/pubmed/35008599
http://dx.doi.org/10.3390/ijms23010173